News & Events

New research shows children with blood cancer at low risk of severe COVID-19 disease

Research published in the British Medical Journal’s Archives of Disease in Childhood has shown that children with haematological malignancies (blood cancers) are at no higher risk of severe COVID-19 disease than children with other types of cancer. Previously published research from this project had shown that overall, children with cancer were at no higher risk of severe disease as a result of infection by the SARS-CoV2 virus than healthy children.

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Can leukemia in children with Down syndrome be prevented? Princess Margaret Scientists reveal a new target that suggests it can

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IMAGE: DR. ELVIN WAGENBLAST, POST-DOCTORAL FELLOW AT THE PRINCESS MARGARET CANCER CENTRE, UNIVERSITY HEALTH NETWORK, IS THE FIRST AUTHOR. view more

CREDIT: UHN

For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down syndrome in preclinical models, paving the way to potentially prevent this cancer in the future.

Children with Down syndrome have a 150-fold increased risk of developing myeloid leukemia within the first five years of their life. Yet the mechanism by which the extra copy of chromosome 21 predisposes to leukemia remains unclear.

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Dr. Google is not your friend

It’s incredible that we live in a world where we can search our symptoms online and within seconds, we’re given thousands of suggestions as to what we are dealing with. But it can also be a cancer survivor’s worst enemy. Most of the symptoms people suffer from as side-effects from cancer treatment will align with any other number of cancers and can lead you down a rabbit hole of despair if you let it.

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Nursed back to health

Nine years later, not only is Goff cancer-free, she also works as an oncology nurse at C.S. Mott Children’s Hospital — on the same floor where she received cancer treatment as a patient.

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